EGFR/ErbB Inhibition Promotes OPC Maturation up to Axon Engagement by Co-Regulating PIP2 and MBP

Remyelination in the adult brain relies on the reactivation of the Neuronal Precursor Cell (NPC) niche and differentiation into Oligodendrocyte Precursor Cells (OPCs) as well as on OPC maturation into myelinating oligodendrocytes (OLs). These two distinct phases in OL development are defined by tran...

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Détails bibliographiques
Publié dans:Cells
Auteurs principaux: Nocita, Emanuela, Del Giovane, Alice, Tiberi, Marta, Boccuni, Laura, Fiorelli, Denise, Sposato, Carola, Romano, Elena, Basoli, Francesco, Trombetta, Marcella, Rainer, Alberto, Traversa, Enrico, Ragnini-Wilson, Antonella
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721729/
https://ncbi.nlm.nih.gov/pubmed/31390799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8080844
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