Determination of the Potential Tumor-Suppressive Effects of Gsdme in a Chemically Induced and in a Genetically Modified Intestinal Cancer Mouse Model

Gasdermin E (GSDME), also known as deafness autosomal dominant 5 (DFNA5) and previously identified to be an inducer of regulated cell death, is frequently epigenetically inactivated in different cancer types, suggesting that GSDME is a tumor suppressor gene. In this study, we aimed to evaluate the t...

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Detaylı Bibliyografya
Yayımlandı:Cancers (Basel)
Asıl Yazarlar: Croes, Lieselot, Fransen, Erik, Hylebos, Marieke, Buys, Kimberly, Hermans, Christophe, Broeckx, Glenn, Peeters, Marc, Pauwels, Patrick, Op de Beeck, Ken, Van Camp, Guy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721630/
https://ncbi.nlm.nih.gov/pubmed/31434357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11081214
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