SRSF2 Mutations in Uveal Melanoma: A Preference for In-Frame Deletions?

Background: Uveal melanoma (UM) is the most common primary ocular malignancy in adults in the Western world. UM with a mutation in SF3B1, a spliceosome gene, is characterized by three or more structural changes of chromosome 1, 6, 8, 9, or 11. Also UM without a mutation in SF3B1 harbors similar chro...

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Detalles Bibliográficos
Publicado en:Cancers (Basel)
Main Authors: van Poppelen, Natasha M., Drabarek, Wojtek, Smit, Kyra N., Vaarwater, Jolanda, Brands, Tom, Paridaens, Dion, Kiliç, Emine, de Klein, Annelies
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
Assuntos:
Communication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721539/
https://ncbi.nlm.nih.gov/pubmed/31426461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11081200
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