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Sprouty3 and Sprouty4, Two Members of a Family Known to Inhibit FGF-Mediated Signaling, Exert Opposing Roles on Proliferation and Migration of Glioblastoma-Derived Cells

Dysregulation of receptor tyrosine kinase-induced pathways is a critical step driving the oncogenic potential of brain cancer. In this study, we investigated the role of two members of the Sprouty (Spry) family in brain cancer-derived cell lines. Using immunoblot analyses we found essential differen...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Celik-Selvi, Burcu Emine, Stütz, Astrid, Mayer, Christoph-Erik, Salhi, Jihen, Siegwart, Gerald, Sutterlüty, Hedwig
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721513/
https://ncbi.nlm.nih.gov/pubmed/31374860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8080808
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