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Targeting Oncogenic BRAF: Past, Present, and Future
Identifying recurrent somatic genetic alterations of, and dependency on, the kinase BRAF has enabled a “precision medicine” paradigm to diagnose and treat BRAF-driven tumors. Although targeted kinase inhibitors against BRAF are effective in a subset of mutant BRAF tumors, resistance to the therapy i...
Gardado en:
| Publicado en: | Cancers (Basel) |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6721448/ https://ncbi.nlm.nih.gov/pubmed/31426419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11081197 |
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