Structural and Aggregation Features of a Human κ-Casein Fragment with Antitumor and Cell-Penetrating Properties

Intrinsically disordered proteins play a central role in dynamic regulatory and assembly processes in the cell. Recently, a human κ-casein proteolytic fragment called lactaptin (8.6 kDa) was found to induce apoptosis of human breast adenocarcinoma MCF-7 and MDA-MB-231 cells with no cytotoxic activit...

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Vydáno v:Molecules
Hlavní autoři: Chinak, Olga A., Shernyukov, Andrey V., Ovcherenko, Sergey S., Sviridov, Evgeniy A., Golyshev, Victor M., Fomin, Alexander S., Pyshnaya, Inna A., Kuligina, Elena V., Richter, Vladimir A., Bagryanskaya, Elena G.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721048/
https://ncbi.nlm.nih.gov/pubmed/31408975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24162919
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