AuNP-M2e + sCpG vaccination of juvenile mice generates lifelong protective immunity to influenza A virus infection

BACKGROUND: Influenza virus infection causes significant morbidity and mortality worldwide. Humans fail to make a universally protective memory response to influenza A because of high mutation rates in the immune-dominant influenza epitopes. We seek the development of a universal influenza A vaccine...

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Gepubliceerd in:Immun Ageing
Hoofdauteurs: Bimler, Lynn, Song, Amber Y., Le, Duy T., Murphy Schafer, Ashleigh, Paust, Silke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720989/
https://ncbi.nlm.nih.gov/pubmed/31507643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-019-0162-y
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