Synthesis, Characterization and Antioxidant Properties of a New Lipophilic Derivative of Edaravone

As part of a program aimed to obtain antioxidants able to interact with cell membrane, edaravone (EdV, 3-methyl-1-phenyl-2-pyrazolin-5-one), a well-known free radical scavenger, has been modified by alkylation at its allylic position (4) with a C-18 hydrocarbon chain, and the increased lipophilicity...

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Vydáno v:Antioxidants (Basel)
Hlavní autoři: Minnelli, Cristina, Laudadio, Emiliano, Galeazzi, Roberta, Rusciano, Dario, Armeni, Tatiana, Stipa, Pierluigi, Cantarini, Mattia, Mobbili, Giovanna
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720979/
https://ncbi.nlm.nih.gov/pubmed/31370225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox8080258
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