Identification of New Inhibitors with Potential Antitumor Activity from Polypeptide Structures via Hierarchical Virtual Screening

Leukemias are neoplasms that affect hematopoietic cells, which are developed by genetic alterations (mutations) that lead to the loss of proliferation control mechanisms (maturation and/or cell death). The α4β1 integrin receptor is a therapeutic target for inflammation, autoimmune diseases and lymph...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Ferreira, Elenilze F. B., Silva, Luciane B., Costa, Glauber V., Costa, Josivan S., Fujishima, Mayara A. T., Leão, Rozires P., Ferreira, André L. S., Federico, Leonardo B., Silva, Carlos H. T. P., Rosa, Joaquín M. C., Macêdo, Williams J. C., Santos, Cleydson B. R.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720962/
https://ncbi.nlm.nih.gov/pubmed/31416180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24162943
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