In Vitro Inhibitory Effects of APINACA on Human Major Cytochrome P450, UDP-Glucuronosyltransferase Enzymes, and Drug Transporters

APINACA (known as AKB48, N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide), an indazole carboxamide synthetic cannabinoid, has been used worldwide as a new psychoactive substance. Drug abusers take various drugs concomitantly, and therefore, it is necessary to characterize the potential of APINACA...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Kim, Sunjoo, Choi, Won-Gu, Kwon, Mihwa, Lee, Sowon, Cho, Yong-Yeon, Lee, Joo Young, Kang, Han Chang, Song, Im-Sook, Lee, Hye Suk
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720883/
https://ncbi.nlm.nih.gov/pubmed/31430908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24163000
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