Blockade of EGFR Activation Promotes TNF-Induced Lung Epithelial Cell Apoptosis and Pulmonary Injury

Pneumonitis is the leading cause of death associated with the use of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) against non-small cell lung cancer (NSCLC). However, the risk factors and the mechanism underlying this toxicity have not been elucidated. Tumor necrosi...

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Publicat a:Int J Mol Sci
Autors principals: Yamaoka, Toshimitsu, Arata, Satoru, Homma, Mayumi, Homma, Tetsuya, Kusumoto, Sojiro, Ando, Koichi, Manabe, Ryou, Kishino, Yasunari, Ohba, Motoi, Tsurutani, Junji, Takimoto, Masafumi, Ohmori, Tohru, Sagara, Hironori
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720446/
https://ncbi.nlm.nih.gov/pubmed/31426531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20164021
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