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MYOD1-Mutant Spindle Cell and Sclerosing Rhabdomyosarcoma: An Aggressive Subtype Irrespective of Age. A Reappraisal for Molecular Classification and Risk Stratification

Sclerosing and spindle cell rhabdomyosarcoma is a rare histologic subtype, designated in the latest WHO classification as a stand-alone pathologic entity. Three genomic groups have been defined: an infantile subset of spindle cell rhabdomyosarcoma harboring VGLL2-related gene fusions, a MYOD1-mutant...

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Detalhes bibliográficos
Publicado no:Mod Pathol
Main Authors: Agaram, Narasimhan P, LaQuaglia, Michael P, Alaggio, Rita, Zhang, Lei, Fujisawa, Yumi, Ladanyi, Marc, Wexler, Leonard, Antonescu, Cristina R
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720105/
https://ncbi.nlm.nih.gov/pubmed/30181563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41379-018-0120-9
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