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An essential role of RNF187 in Notch1 mediated metastasis of hepatocellular carcinoma

BACKGROUND: Aberrant activation of Notch signaling has been causally linked to the metastasis of hepatocellular carcinoma (HCC), however the underlying molecular mechanisms are still poorly understood. RING finger protein 187 (RNF187) was recently revealed to be a driver of several cancers, but its...

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Publicado en:J Exp Clin Cancer Res
Autores principales: Zhang, Lei, Chen, Jiewei, Yong, Juanjuan, Qiao, Liang, Xu, Leibo, Liu, Chao
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720101/
https://ncbi.nlm.nih.gov/pubmed/31477177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1382-x
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