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Regioselective Pd-catalyzed direct C1- and C2-arylations of lilolidine for the access to 5,6-dihydropyrrolo[3,2,1-ij]quinoline derivatives

The Pd-catalyzed C–H bond functionalization of lilolidine was investigated. The use of a palladium-diphosphine catalyst associated to acetate bases in DMA was found to promote the regioselective arylation at α-position of the nitrogen atom of lilolidine with a wide variety of aryl bromides. From the...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Huang, Hai-Yun, Li, Haoran, Roisnel, Thierry, Soulé, Jean-François, Doucet, Henri
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719733/
https://ncbi.nlm.nih.gov/pubmed/31501675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.204
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