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Proton Pump Activation in Stimulated Parietal Cells Is Regulated by Gastric Acid Secretory Capacity: A Human Study

Under normal physiological conditions, gastric acid production is controlled by a negative feedback mechanism. Proton pump inhibitors, such as pantoprazole, inhibit gastric acid secretion by irreversibly binding and inactivating luminally active hydrogen potassium ATPase. Recovery of acid production...

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Bibliografiske detaljer
Udgivet i:J Clin Pharmacol
Main Authors: Metz, David C., Ferron, Geraldine M., Paul, Jeffrey, Turner, Mary Beth, Soffer, Elaine, Pisegna, Joseph R., Bochenek, Wieslaw J.
Format: Artigo
Sprog:Inglês
Udgivet: 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719691/
https://ncbi.nlm.nih.gov/pubmed/12017345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/00912700222011562
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