Death-Associated Protein Kinase Controls STAT3 Activity in Intestinal Epithelial Cells

The TNF–IL-6–STAT3 pathway plays a crucial role in promoting ulcerative colitis-associated carcinoma (UCC). To date, the negative regulation of STAT3 is poorly understood. Interestingly, intestinal epithelial cells of UCC in comparison to ulcerative colitis show high expression levels of anti-inflam...

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Veröffentlicht in:Am J Pathol
Hauptverfasser: Chakilam, Saritha, Gandesiri, Muktheshwar, Rau, Tilman T., Agaimy, Abbas, Vijayalakshmi, Mahadevan, Ivanovska, Jelena, Wirtz, Ralph M., Schulze-Luehrmann, Jan, Benderska, Natalya, Wittkopf, Nadine, Chellappan, Ajithavalli, Ruemmele, Petra, Vieth, Michael, Rave-Fränk, Margret, Christiansen, Hans, Hartmann, Arndt, Neufert, Clemens, Atreya, Raja, Becker, Christoph, Steinberg, Pablo, Schneider-Stock, Regine
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719660/
https://ncbi.nlm.nih.gov/pubmed/23438478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.11.026
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