Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5

Cells continuously adapt cellular processes by integrating external and internal signals. In yeast, multiple stress signals regulate pheromone signaling to prevent mating under unfavorable conditions. However, the underlying crosstalk mechanisms remain poorly understood. Here, we show that mechanica...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: van Drogen, Frank, Mishra, Ranjan, Rudolf, Fabian, Walczak, Michal J., Lee, Sung Sik, Reiter, Wolfgang, Hegemann, Björn, Pelet, Serge, Dohnal, Ilse, Binolfi, Andres, Yudina, Zinaida, Selenko, Philipp, Wider, Gerhard, Ammerer, Gustav, Peter, Matthias
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2019
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719448/
https://ncbi.nlm.nih.gov/pubmed/31315942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201808161
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