Unmethylated Insulin as an Adjunctive Marker of Beta Cell Death and Progression to Type 1 Diabetes in Participants at Risk for Diabetes

Islet autoantibody (iAb)-positive individuals have a high risk of progression to type 1 diabetes (T1D), although the rate of progression is highly variable and factors involved in the rate of progression are largely unknown. The ratio of unmethylated/methylated insulin DNA levels (unmethylated INS r...

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Publicado en:Int J Mol Sci
Autores principales: Simmons, Kimber M., Fouts, Alexandra, Pyle, Laura, Clark, Pamela, Dong, Fran, Yu, Liping, Usmani-Brown, Sahar, Gottlieb, Peter, Herold, Kevan C., Steck, Andrea K.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719233/
https://ncbi.nlm.nih.gov/pubmed/31398795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20163857
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