Sex-specific transcriptional and proteomic signatures in schizophrenia

It has remained unclear why schizophrenia typically manifests after adolescence and which neurobiological mechanisms are underlying the cascade leading to the actual onset of the illness. Here we show that the use of induced pluripotent stem cell-derived neurons of monozygotic twins from pairs disco...

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Publicado en:Nat Commun
Main Authors: Tiihonen, Jari, Koskuvi, Marja, Storvik, Markus, Hyötyläinen, Ida, Gao, Yanyan, Puttonen, Katja A., Giniatullina, Raisa, Poguzhelskaya, Ekaterina, Ojansuu, Ilkka, Vaurio, Olli, Cannon, Tyrone D., Lönnqvist, Jouko, Therman, Sebastian, Suvisaari, Jaana, Kaprio, Jaakko, Cheng, Lesley, Hill, Andrew F., Lähteenvuo, Markku, Tohka, Jussi, Giniatullin, Rashid, Lehtonen, Šárka, Koistinaho, Jari
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718673/
https://ncbi.nlm.nih.gov/pubmed/31477693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11797-3
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