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Gene set enrichment analysis to create polygenic scores: a developmental examination of aggression
Previous approaches for creating polygenic risk scores (PRSs) do not explicitly consider the biological or developmental relevance of the genetic variants selected for inclusion. We applied gene set enrichment analysis to meta-GWAS data to create developmentally targeted, functionally informed PRSs....
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| Publicado no: | Transl Psychiatry |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6718657/ https://ncbi.nlm.nih.gov/pubmed/31477688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-019-0513-7 |
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