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Early‐onset aging and mitochondrial defects associated with loss of histone acetyltransferase 1 (Hat1)
Histone acetyltransferase 1 (Hat1) is responsible for the acetylation of newly synthesized histone H4 on lysines 5 and 12 during the process of chromatin assembly. To understand the broader biological role of Hat1, we have generated a conditional mouse knockout model of this enzyme. We previously re...
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| Publicado no: | Aging Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6718594/ https://ncbi.nlm.nih.gov/pubmed/31290578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12992 |
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