PGC‐1a integrates a metabolism and growth network linked to caloric restriction

Deleterious changes in energy metabolism have been linked to aging and disease vulnerability, while activation of mitochondrial pathways has been linked to delayed aging by caloric restriction (CR). The basis for these associations is poorly understood, and the scope of impact of mitochondrial activ...

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Veröffentlicht in:Aging Cell
Hauptverfasser: Miller, Karl N., Clark, Josef P., Martin, Stephen A., Howell, Porsha R., Burhans, Maggie S., Haws, Spencer A., Johnson, Nathan B., Rhoads, Timothy W, Pavelec, Derek M., Eliceiri, Kevin W., Roopra, Avtar S., Ntambi, James M., Denu, John M., Parks, Brian W., Anderson, Rozalyn M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718593/
https://ncbi.nlm.nih.gov/pubmed/31267675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12999
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