Forkhead box O3 protects the heart against paraquat‐induced aging‐associated phenotypes by upregulating the expression of antioxidant enzymes

Paraquat (PQ) promotes cell senescence in brain tissue, which contributes to Parkinson's disease. Furthermore, PQ induces heart failure and oxidative damage, but it remains unknown whether and how PQ induces cardiac aging. Here, we demonstrate that PQ induces phenotypes associated with senescen...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Chang, Zao‐Shang, Xia, Jing‐Bo, Wu, Hai‐Yan, Peng, Wen‐Tao, Jiang, Fu‐Qing, Li, Jing, Liang, Chi‐Qian, Zhao, Hui, Park, Kyu‐Sang, Song, Guo‐Hua, Kim, Soo‐Ki, Huang, Ruijin, Zheng, Li, Cai, Dong‐Qing, Qi, Xu‐Feng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718552/
https://ncbi.nlm.nih.gov/pubmed/31264342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12990
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