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IL-23/IL-17 Axis Activates IL-1β-Associated Inflammasome in Macrophages and Generates an Auto-Inflammatory Response in a Subgroup of Patients With Bullous Pemphigoid

Bullous Pemphigoid (BP) is a skin autoimmune blistering disease characterized by immune-mediated degradation of the dermo-epidermal junction and release of a large number of inflammatory cytokines. Interleukin-1β (IL-1β) is a pleiotropic pro-inflammatory cytokine associated with inflammasome activat...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Le Jan, Sébastien, Muller, Céline, Plee, Julie, Durlach, Anne, Bernard, Philippe, Antonicelli, Frank
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718471/
https://ncbi.nlm.nih.gov/pubmed/31507596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01972
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