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HBV-Induced Immune Imbalance in the Development of HCC

Chronic hepatitis B virus (HBV) infection is one of the high-risk factors for human HCC. Despite the integration of virus DNA and the oncoprotein HBx, chronic necroinflammation and hepatocellular regeneration account for hepatocarcinogenesis. As a non-cytopathic virus, HBV is extensively recognized...

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Pubblicato in:Front Immunol
Autori principali: Chen, Yongyan, Tian, Zhigang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718466/
https://ncbi.nlm.nih.gov/pubmed/31507621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02048
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