Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome

Natural killer (NK) cells are critical to both innate and adaptive immunity. However, the development and heterogeneity of human NK cells are yet to be fully defined. Using single-cell RNA-sequencing technology, here we identify distinct NK populations in human bone marrow and blood, including one p...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yang, Chao, Siebert, Jason R., Burns, Robert, Gerbec, Zachary J., Bonacci, Benedetta, Rymaszewski, Amy, Rau, Mary, Riese, Matthew J., Rao, Sridhar, Carlson, Karen-Sue, Routes, John M., Verbsky, James W., Thakar, Monica S., Malarkannan, Subramaniam
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718415/
https://ncbi.nlm.nih.gov/pubmed/31477722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11947-7
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