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Nuphar alkaloids induce very rapid apoptosis through a novel caspase dependent but BAX/BAK independent pathway

Nuphar alkaloids, originally isolated from water lilies, induce apoptosis in mammalian cells in less than one hour, making them possibly the fastest known inducers. However, the mechanism by which this rapid apoptosis occurs remains unknown. We have investigated canonical aspects of apoptosis to det...

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Detalhes bibliográficos
Publicado no:Cell Biol Toxicol
Main Authors: Mallick, David J., Korotkov, Alexander, Li, Hui, Wu, Jimmy, Eastman, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718348/
https://ncbi.nlm.nih.gov/pubmed/30826899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10565-019-09469-5
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