Development and analytical validation of a next-generation sequencing based microsatellite instability (MSI) assay

BACKGROUND: We have developed and analytically validated a next-generation sequencing (NGS) assay to classify microsatellite instability (MSI) in formalin-fixed paraffin-embedded (FFPE) tumor specimens. METHODOLOGY: The assay relies on DNA-seq evaluation of insertion/deletion (indel) variability at...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Pabla, Sarabjot, Andreas, Jonathan, Lenzo, Felicia L., Burgher, Blake, Hagen, Jacob, Giamo, Vincent, Nesline, Mary K., Wang, Yirong, Gardner, Mark, Conroy, Jeffrey M., Papanicolau-Sengos, Antonios, Morrison, Carl, Glenn, Sean T.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718258/
https://ncbi.nlm.nih.gov/pubmed/31497248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27142
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