Structure of GTP cyclohydrolase I from Listeria monocytogenes, a potential anti-infective drug target

A putative open reading frame encoding GTP cyclohydrolase I from Listeria monocytogenes was expressed in a recombinant Escherichia coli strain. The recombinant protein was purified and was confirmed to convert GTP to dihydroneopterin triphosphate (K (m) = 53 µM; v (max) = 180 nmol mg(−1) min(−1)). T...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Schüssler, Sonja, Haase, Ilka, Perbandt, Markus, Illarionov, Boris, Siemens, Alexandra, Richter, Klaus, Bacher, Adelbert, Fischer, Markus, Gräwert, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2019
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718149/
https://ncbi.nlm.nih.gov/pubmed/31475925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X19010902
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