SALM1 controls synapse development by promoting F‐actin/PIP2‐dependent Neurexin clustering

Synapse development requires spatiotemporally regulated recruitment of synaptic proteins. In this study, we describe a novel presynaptic mechanism of cis‐regulated oligomerization of adhesion molecules that controls synaptogenesis. We identified synaptic adhesion‐like molecule 1 (SALM1) as a constit...

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Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: Brouwer, Marinka, Farzana, Fatima, Koopmans, Frank, Chen, Ning, Brunner, Jessie W, Oldani, Silvia, Li, Ka Wan, van Weering, Jan RT, Smit, August B, Toonen, Ruud F, Verhage, Matthijs
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717895/
https://ncbi.nlm.nih.gov/pubmed/31368584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101289
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