Identification of phospholipase C β downstream effect on transient receptor potential canonical 1/4, transient receptor potential canonical 1/5 channels

Gα(q)-coupled receptor stimulation was implied in the activation process of transient receptor potential canonical (TRPC)1/4 and TRPC1/5 heterotetrameric channels. The inactivation occurs due to phosphatidylinositol 4,5-biphosphate (PI(4,5)P(2)) depletion. When PI(4,5)P(2) depletion was induced by m...

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Pubblicato in:Korean J Physiol Pharmacol
Autori principali: Ko, Juyeon, Myeong, Jongyun, Kwak, Misun, Jeon, Ju-Hong, So, Insuk
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Physiological Society and The Korean Society of Pharmacology 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717798/
https://ncbi.nlm.nih.gov/pubmed/31496873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2019.23.5.357
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