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RAC1 inhibition reverses cisplatin resistance in esophageal squamous cell carcinoma and induces downregulation of glycolytic enzymes

Development of chemoresistance remains a major challenge in treating esophageal squamous cell carcinoma (ESCC) patients despite treatment advances. However, the role of RAC1 in chemoresistance of ESCC and the underlying mechanisms remain largely unknown. In this study, we found that higher levels of...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Zeng, Rui‐Jie, Zheng, Chun‐Wen, Gu, Jing‐E, Zhang, Hai‐Xia, Xie, Lei, Xu, Li‐Yan, Li, En‐Min
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717762/
https://ncbi.nlm.nih.gov/pubmed/31314174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12548
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