A pathway linking translation stress to checkpoint kinase 2 signaling in Neurospora crassa

Checkpoint kinase 2 (CHK-2) is a key component of the DNA damage response (DDR). CHK-2 is activated by the PIP3-kinase-like kinases (PI3KKs) ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related protein (ATR), and in metazoan also by DNA-dependent protein kinase catalytic su...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Diernfellner, Axel C. R., Lauinger, Linda, Shostak, Anton, Brunner, Michael
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
PNAS Plus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717302/
https://ncbi.nlm.nih.gov/pubmed/31413202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815396116
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