Amplification of 9p24.1 in diffuse large B-cell lymphoma identifies a unique subset of cases that resemble primary mediastinal large B-cell lymphoma

Copy number alterations (CNAs) of 9p24.1 occur frequently in Hodgkin lymphoma, primary mediastinal large B-cell lymphoma (PMBCL), primary central nervous system lymphoma, and primary testicular lymphoma, resulting in overexpression of PD-L1 and sensitivity to PD-1 blockade-based immunotherapy. While...

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Опубликовано в: :Blood Cancer J
Главные авторы: Wang, Yucai, Wenzl, Kerstin, Manske, Michelle K., Asmann, Yan W., Sarangi, Vivekananda, Greipp, Patricia T., Krull, Jordan E., Hartert, Keenan, He, Rong, Feldman, Andrew L., Maurer, Matthew J., Slager, Susan L., Nowakowski, Grzegorz S., Habermann, Thomas M., Witzig, Thomas E., Link, Brian K., Ansell, Stephen M., Cerhan, James R., Novak, Anne J.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717207/
https://ncbi.nlm.nih.gov/pubmed/31471540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-019-0233-5
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