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Scleroderma patients with antibodies against the large subunits of both RNA polymerases-I and -III are protected against cancer

OBJECTIVES: While compelling data suggest a cancer-induced autoimmunity model in scleroderma patients with anti-RNA polymerase III large subunit (anti-RPC155) antibodies, ~85% of these patients do not manifest cancer. We hypothesized that anti-RPC155-positive scleroderma patients without detectable...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Shah, Ami A., Laiho, Marikki, Rosen, Antony, Casciola-Rosen, Livia
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717013/
https://ncbi.nlm.nih.gov/pubmed/30888702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40893
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