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Non-invasive Imaging of Oxygen Concentration in a Complex In Vitro Biofilm Infection Model Using (19)F MRI: Persistence of an Oxygen Sink Despite Prolonged Antibiotic Therapy

PURPOSE: Oxygen availability is a critical determinant of microbial biofilm activity and antibiotic susceptibility. However, measuring oxygen gradients in these systems remains difficult, with the standard microelectrode approach being both invasive and limited to single-point measurement. The goal...

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Detalhes bibliográficos
Publicado no:Magn Reson Med
Main Authors: Simkins, Jeffrey W., Stewart, Philip S., Codd, Sarah L., Seymour, Joseph D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716988/
https://ncbi.nlm.nih.gov/pubmed/31373035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.27888
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