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Methylenetetrahydrofolate Reductase Polymorphism and Premature Coronary Artery Disease

Methylenetetrahydrofolate reductase (MTHFR) catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine re-methylation to methionine. Its deficiency leads to an increased serum level of homocysteine, which is well-known to be associated wit...

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Détails bibliographiques
Publié dans:Cureus
Auteurs principaux: Zaghloul, Ahmed, Iorgoveanu, Corina, Desai, Aakash, Balakumaran, Kathir, Chen, Kai
Format: Artigo
Langue:Inglês
Publié: Cureus 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716763/
https://ncbi.nlm.nih.gov/pubmed/31497444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7759/cureus.5014
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