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Design of modular gellan gum hydrogel functionalized with avidin and biotinylated adhesive ligands for cell culture applications

This article proposes the coupling of the recombinant protein avidin to the polysaccharide gellan gum to create a modular hydrogel substrate for 3D cell culture and tissue engineering. Avidin is capable of binding biotin, and thus biotinylated compounds can be tethered to the polymer network to impr...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Gering, Christine, Koivisto, Janne T., Parraga, Jenny, Leppiniemi, Jenni, Vuornos, Kaisa, Hytönen, Vesa P., Miettinen, Susanna, Kellomäki, Minna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716642/
https://ncbi.nlm.nih.gov/pubmed/31469884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221931
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