Prevalence of resistance associated substitutions and efficacy of baseline resistance-guided chronic hepatitis C treatment in Spain from the GEHEP-004 cohort

Treatment guidelines differ in their recommendation to determine baseline resistance associated substitutions (RAS) before starting a first-line treatment with direct-acting antivirals (DAAs). Here we analyze the efficacy of DAA treatment with baseline RAS information. We conducted a prospective stu...

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Pubblicato in:PLoS One
Autori principali: Pérez, Ana Belén, Chueca, Natalia, Macías, Juan, Pineda, Juan Antonio, Salmerón, Javier, Rivero-Juárez, Antonio, Hidalgo-Tenorio, Carmen, Espinosa, María Dolores, Téllez, Francisco, Von-Wichmann, Miguel Ángel, Omar, Mohamed, Santos, Jesús, Hernández-Quero, José, Antón, José Joaquin, Collado, Antonio, Lozano, Ana Belén, García-Deltoro, Miguel, Casado, Marta, Pascasio, Juan Manuel, Selfa, Aida, Rosales, José Miguel, De la Iglesia, Alberto, Arenas, Juan Ignacio, García-Bujalance, Silvia, Ríos, María José, Bernal, Enrique, Martínez, Onofre, García-Herola, Antonio, Vélez, Mónica, Rincón, Pilar, García, Federico
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716636/
https://ncbi.nlm.nih.gov/pubmed/31469856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221231
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