Deletion of GLUT1 in mouse lens epithelium leads to cataract formation.

The primary energy substrate of the lens is glucose and uptake of glucose from the aqueous humor is dependent on glucose transporters. GLUT1, the facilitated glucose transporter encoded by Slc2a1 is expressed in the epithelium of bovine, human and rat lenses. In the current study, we examined the ex...

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Veröffentlicht in:Exp Eye Res
Hauptverfasser: Swarup, Aditi, Bell, Brent A., Du, Jianhai, Han, John Y. S., Soto, Jamie, Abel, E. Dale, Bravo-Nuevo, Arturo, FitzGerald, Paul G., Peachey, Neal S., Philp, Nancy J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716165/
https://ncbi.nlm.nih.gov/pubmed/29604281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2018.03.021
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