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Conformational heterogeneity in human interphase chromosome organization reconciles the FISH and Hi-C paradox
Hi-C experiments are used to infer the contact probabilities between loci separated by varying genome lengths. Contact probability should decrease as the spatial distance between two loci increases. However, studies comparing Hi-C and FISH data show that in some cases the distance between one pair o...
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| Udgivet i: | Nat Commun |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6715811/ https://ncbi.nlm.nih.gov/pubmed/31467267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11897-0 |
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