Maximizing binary interactome mapping with a minimal number of assays

Complementary assays are required to comprehensively map complex biological entities such as genomes, proteomes and interactome networks. However, how various assays can be optimally combined to approach completeness while maintaining high precision often remains unclear. Here, we propose a framewor...

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Udgivet i:Nat Commun
Main Authors: Choi, Soon Gang, Olivet, Julien, Cassonnet, Patricia, Vidalain, Pierre-Olivier, Luck, Katja, Lambourne, Luke, Spirohn, Kerstin, Lemmens, Irma, Dos Santos, Mélanie, Demeret, Caroline, Jones, Louis, Rangarajan, Sudharshan, Bian, Wenting, Coutant, Eloi P., Janin, Yves L., van der Werf, Sylvie, Trepte, Philipp, Wanker, Erich E., De Las Rivas, Javier, Tavernier, Jan, Twizere, Jean-Claude, Hao, Tong, Hill, David E., Vidal, Marc, Calderwood, Michael A., Jacob, Yves
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715725/
https://ncbi.nlm.nih.gov/pubmed/31467278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11809-2
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