DNA methylation silencing of microRNA gene methylator in the precancerous background mucosa with and without gastric cancer: Analysis of the effects of H. pylori eradication and long-term aspirin use

The risk of gastric cancer (GC) declines after Helicobacter pylori (H. pylori) eradication and long-term aspirin use. We evaluated the effects of H. pylori eradication (Cohort 1) and aspirin use (Cohort 2) on the methylation of microRNAs (miRNAs), such as miR-34c, miR-124a-3, miR-129-2, and miR-137,...

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Publicado no:Sci Rep
Main Authors: Watari, Jiro, Ito, Chiyomi, Shimoda, Tadakazu, Tomita, Toshihiko, Oshima, Tadayuki, Fukui, Hirokazu, Das, Kiron M., Miwa, Hiroto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715663/
https://ncbi.nlm.nih.gov/pubmed/31467363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49069-1
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