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The role of mycophenolate in the treatment of antineutrophil cytoplasmic antibody-associated vasculitis

Mycophenolic acid, the active metabolite for mycophenolate mofetil and mycophenolic sodium, is a strong, noncompetitive, reversible inhibitor of inosine monophosphate dehydrogenase, the key enzyme in de novo synthesis of guanosine nucleotides leading to selective inhibition of lymphocyte proliferati...

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Podrobná bibliografie
Vydáno v:World J Nephrol
Hlavní autoři: Koukoulaki, Maria, Iatrou, Christos
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Inc 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715575/
https://ncbi.nlm.nih.gov/pubmed/31523631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5527/wjn.v8.i4.75
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