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The role of mycophenolate in the treatment of antineutrophil cytoplasmic antibody-associated vasculitis
Mycophenolic acid, the active metabolite for mycophenolate mofetil and mycophenolic sodium, is a strong, noncompetitive, reversible inhibitor of inosine monophosphate dehydrogenase, the key enzyme in de novo synthesis of guanosine nucleotides leading to selective inhibition of lymphocyte proliferati...
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| Published in: | World J Nephrol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Baishideng Publishing Group Inc
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6715575/ https://ncbi.nlm.nih.gov/pubmed/31523631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5527/wjn.v8.i4.75 |
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