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Coupling adaptive molecular evolution to phylodynamics using fitness-dependent birth-death models
Beneficial and deleterious mutations cause the fitness of lineages to vary across a phylogeny and thereby shape its branching structure. While standard phylogenetic models do not allow mutations to feedback and shape trees, birth-death models can account for this feedback by letting the fitness of l...
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| Publié dans: | eLife |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6715349/ https://ncbi.nlm.nih.gov/pubmed/31411558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45562 |
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