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An estimator of first coalescent time reveals selection on young variants and large heterogeneity in rare allele ages among human populations

Allele age has long been a focus of population genetic research, primarily because it can be an important clue to the fitness effects of an allele. By virtue of their effects on fitness, alleles under directional selection are expected to be younger than neutral alleles of the same frequency. We dev...

詳細記述

保存先:
書誌詳細
出版年:PLoS Genet
主要な著者: Platt, Alexander, Pivirotto, Alyssa, Knoblauch, Jared, Hey, Jody
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715256/
https://ncbi.nlm.nih.gov/pubmed/31425500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008340
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