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Polymorphisms C677T and A1298C of MTHFR Gene: Homocysteine Levels and Prothrombotic Biomarkers in Coronary and Pulmonary Thromboembolic Disease

The activity of the enzyme methylenetetrahydrofolate reductase (MTHFR) determines homocysteine (Hcy) levels, and polymorphisms in its gene affect the activity of the enzyme. Changes in the enzyme’s activity may lead to a higher susceptibility to develop arterial and venous thromboembolic disease. Th...

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Bibliografiske detaljer
Udgivet i:Clin Appl Thromb Hemost
Main Authors: Lupi-Herrera, Eulo, Soto-López, María Elena, Lugo-Dimas, Antonio de Jesús, Núñez-Martínez, Marcela Elizabeth, Gamboa, Ricardo, Huesca-Gómez, Claudia, Sierra-Galán, Lilia Mercedes, Guarner-Lans, Verónica
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714945/
https://ncbi.nlm.nih.gov/pubmed/29916259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1076029618780344
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