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Derivation and Validation of Age- and Body Mass Index-Adjusted Weight-Based Unfractionated Heparin Dosing

Unfractionated heparin dosing is unpredictable and subject to numerous pharmacokinetic changes including distribution and metabolic changes associated with obesity and age. Weight-based dosing is commonly used to better predict the dose for a patient when targeting a therapeutic range. A dosing equa...

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Detalhes bibliográficos
Publicado no:Clin Appl Thromb Hemost
Main Authors: Schurr, James W., Muske, Anne-Marie, Stevens, Craig A., Culbreth, Sarah E., Sylvester, Katelyn W., Connors, Jean M.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714904/
https://ncbi.nlm.nih.gov/pubmed/30841720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1076029619833480
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