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Concomitant Use of Proton-Pump Inhibitors and Clopidogrel Increases the Risk of Adverse Outcomes in Patients With Ischemic Stroke Carrying Reduced-Function CYP2C19*2

OBJECTIVE: Conflicting data exist as to whether proton-pump inhibitors (PPIs) diminish the efficacy of clopidogrel. The aim of this study was to investigate the association between cytochrome P450 (CYP) genetic variants and clinical adverse outcomes of concomitant use of PPIs and clopidogrel by pati...

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Detalhes bibliográficos
Publicado no:Clin Appl Thromb Hemost
Main Authors: Yi, Xingyang, Han, Zhao, Zhou, Qiang, Cheng, Wen, Lin, Jing, Wang, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714622/
https://ncbi.nlm.nih.gov/pubmed/27637911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1076029616669787
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