Hepatic Bioactivation of Skin-Sensitizing Drugs to Immunogenic Reactive Metabolites

[Image: see text] The clinical use of some drugs, such as carbamazepine, phenytoin, and allopurinol, is often associated with adverse cutaneous reactions. The bioactivation of drugs into immunologically reactive metabolites by the liver is postulated to be the first step in initiating a downstream c...

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Xehetasun bibliografikoak
Argitaratua izan da:ACS Omega
Egile Nagusiak: Chong, Lor Huai, Ng, Celine, Li, Huan, Tian, Edmund Feng, Ananthanarayanan, Abhishek, McMillian, Michael, Toh, Yi-Chin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2019
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714514/
https://ncbi.nlm.nih.gov/pubmed/31497708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b01551
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